Stiff Person Syndrome

Aaron E. Miller and Teresa M. DeAngelis

in Neuroimmunology

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780199732920
Published online April 2013 | e-ISBN: 9780199322862 | DOI:

Series: What Do I Do Now

Stiff Person Syndrome

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Stiff person syndrome is an important autoimmune mediated disorder to consider in patients with unexplained pain and muscular rigidity. We review the proposed diagnostic criteria, common clinical features, and important serologic and electrophysiological tests to aid in diagnosis as well as medical and rehabilitative therapeutic options. In addition, we discuss the identification and management of possible paraneoplastic presentations.

Chapter.  1490 words. 

Subjects: Neurology

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