Chapter

Phasic GABA<sub>A</sub>-Mediated Inhibition

Enrico Cherubini

in Jasper's Basic Mechanisms of the Epilepsies

Fourth edition

Published on behalf of ©Jeffrey L. Noebels, Massimo Avoli, Michael A. Rogawski, Richard W. Olsen, and Antonio V. Delgado-Escueta

Published in print July 2012 | ISBN: 9780199746545
Published online April 2013 | e-ISBN: 9780199322817 | DOI: http://dx.doi.org/10.1093/med/9780199746545.003.0008

Series: Contemporary Neurology Series

Phasic GABAA-Mediated Inhibition

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This review will focus on GABAA-mediated phasic inhibition which, in physiological conditions, exerts a powerful control on cell excitability and network oscillations thought to be associated with higher cognitive functions.3 An impairment of fast GABAergic signaling is involved in various psychiatric and neurological disorders including epilepsy.4

Chapter.  7883 words.  Illustrated.

Subjects: Neurology

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