Chapter

Glia–Neuron Interactions in Ictogenesis and Epileptogenesis

Annamaria Vezzani, Stephan Auvin, Teresa Ravizza and Eleonora Aronica

in Jasper's Basic Mechanisms of the Epilepsies

Fourth edition

Published on behalf of ©Jeffrey L. Noebels, Massimo Avoli, Michael A. Rogawski, Richard W. Olsen, and Antonio V. Delgado-Escueta

Published in print July 2012 | ISBN: 9780199746545
Published online April 2013 | e-ISBN: 9780199322817 | DOI: http://dx.doi.org/10.1093/med/9780199746545.003.0048

Series: Contemporary Neurology Series

Glia–Neuron Interactions in Ictogenesis and Epileptogenesis

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This chapter reports clinical observations in drug-resistant epilepsies and experimental findings in adult and immature rodent models of seizures and epileptogenesis that causally link brain inflammation to the epileptic process. We discuss the role of specific inflammatory mediators of glia–neuron communication in the etiopathogenesis of seizures.

Chapter.  10226 words.  Illustrated.

Subjects: Neurology

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