Chapter

Myoclonin1/EFHC1 in Cell Division, Neuroblast Migration, and Synapse/Dendrite Formation in Juvenile Myoclonic Epilepsy

Thierry Grisar, Bernard Lakaye, Laurence de Nijs, Joseph J. LoTurco, Andrea Daga and Antonio V. Delgado-Escueta

in Jasper's Basic Mechanisms of the Epilepsies

Fourth edition

Published on behalf of ©Jeffrey L. Noebels, Massimo Avoli, Michael A. Rogawski, Richard W. Olsen, and Antonio V. Delgado-Escueta

Published in print July 2012 | ISBN: 9780199746545
Published online April 2013 | e-ISBN: 9780199322817 | DOI: http://dx.doi.org/10.1093/med/9780199746545.003.0067

Series: Contemporary Neurology Series

Myoclonin1/EFHC1 in Cell Division, Neuroblast Migration, and Synapse/Dendrite Formation in Juvenile Myoclonic Epilepsy

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In this chapter , we review these putative roles of Myoclonin 1/EFHC1 during brain development and during adulthood. We posit the hypothesis that JME is a developmental disease involving neuronal migration and synaptic bouton and dendritic morphogenesis.

Chapter.  9311 words.  Illustrated.

Subjects: Neurology

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