Chapter

Synaptic and Channel Antibodies

Robert B. Darnell and Jerome B. Posner

in Paraneoplastic Syndromes

Published on behalf of Oxford University Press

Published in print April 2010 | ISBN: 9780199772735
Published online April 2013 | e-ISBN: 9780199322916 | DOI: http://dx.doi.org/10.1093/med/9780199772735.003.013

Series: Contemporary Neurology Series

Synaptic and Channel Antibodies

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This chapter addresses antibodies whose antigen is either at the synapse or on the surface of nerves or muscles where they serve as channels that allow the entry of ions or other substances into the cell. The importance of the cell-surface antigens is that their function can be directly perturbed by antibodies. Accordingly, B-cells probably play an important role in the pathogenesis of most of these disorders. Table 13–1 lists the antibodies considered in this chapter.

Chapter.  18647 words.  Illustrated.

Subjects: Neurology

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