Vancomycin Adult Dosing and Monitoring

John W. Wilson and Lynn L. Estes

in Mayo Clinic Antimicrobial Therapy

Second edition

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print November 2011 | ISBN: 9780199797783
Published online June 2012 | e-ISBN: 9780199929658 | DOI:

Series: Mayo Clinic Scientific Press

Vancomycin Adult Dosing and Monitoring

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(Note: Several vancomycin dosing and monitoring protocols exist; this is the one used at Mayo Clinic.)

Loading dose: Consider 20–30 mg/kg, especially in critically ill patients with serious infections such as meningitis, health care–associated pneumonia, or endocarditis.

Maintenance dose: Give 15–20 mg/kg based on actual body weight for most patients (20 mg/kg is reasonable when aiming for a trough range of 15–20 mcg/mL). Adjust based on serum levels. See also the following sections on hemodialysis and continuous renal replacement therapy....

Chapter.  1592 words. 

Subjects: Infectious Diseases

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