Chapter

Select Anaerobic Bacteria: <i>Clostridium tetani</i> and <i>Clostridium botulinum</i>

M. Rizwan Sohail

in Mayo Clinic Infectious Diseases Board Review

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print January 2012 | ISBN: 9780199827626
Published online June 2012 | e-ISBN: 9780199929641 | DOI: http://dx.doi.org/10.1093/med/9780199827626.003.0008

Series: Mayo Clinic Scientific Press

Select Anaerobic Bacteria: Clostridium tetani and Clostridium botulinum

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The focus of this chapter is 2 types of gram-negative aerobic bacteria, Clostridium tetani and Clostridium botulinum, and the diseases they cause. Tetanus is a nervous system disorder characterized by intense, painful muscle spasm caused by Clostridium tetani. Tetanus is prevalent in developing countries, but it is rare in developed nations owing to universal childhood vaccination. Common modes of acquisition are puncture wounds, gunshot wounds, burns, compound fractures, and contaminated or unsterile injections. Botulism is a neuroparalytic syndrome caused by neurotoxin produced by Clostridium botulinum. The US Food and Drug Administration approved botulinum toxin for treatment of neuromuscular disorders, including blepharospasm, strabismus, and torticollis, and for many cosmetic procedures.

Chapter.  3259 words.  Illustrated.

Subjects: Infectious Diseases

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