Histoplasma capsulatum

Janis E. Blair

in Mayo Clinic Infectious Diseases Board Review

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print January 2012 | ISBN: 9780199827626
Published online June 2012 | e-ISBN: 9780199929641 | DOI:

Series: Mayo Clinic Scientific Press

Histoplasma capsulatum

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Histoplasmosis is caused by Histoplasma capsulatum, one of the most common opportunistic infections in persons with AIDS. Varieties include Histoplasma capsulatum var capsulatum and Histoplasma capsulatum var duboisii (Histoplasma duboisii).

Histoplasma capsulatum var capsulatum causes histoplasmosis in the Americas, parts of Africa, eastern Asia, and Australia rarely, in Europe. Histoplasma capsulatum var duboisii (Histoplasma duboisii) causes African histoplasmosis, which occurs only in Africa between the Tropic of Cancer and the Tropic of Capricorn and on the island of Madagascar. It manifests as a subacute granuloma of the skin or bone but may disseminate to the skin, lymph nodes, bones, joints, lungs, and abdomen.

Chapter.  2350 words.  Illustrated.

Subjects: Infectious Diseases

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