Chapter

<i>Coccidioides</i> Species

Janis E Blair

in Mayo Clinic Infectious Diseases Board Review

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print January 2012 | ISBN: 9780199827626
Published online June 2012 | e-ISBN: 9780199929641 | DOI: http://dx.doi.org/10.1093/med/9780199827626.003.0017

Series: Mayo Clinic Scientific Press

Coccidioides Species

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Coccidioidomycosis is endemic only in the Western Hemisphere, mainly in southern Arizona, New Mexico, Texas, and much of central and southern California, and in small areas in South American countries, including Argentina, Brazil, Colombia, Paraguay, and Venezuela. It is highly endemic in northern Mexico. The organism grows in soil in a semiarid, geographically restricted region, the Lower Sonoran Life Zone. Two nearly identical species cause coccidioidomycosis: Coccidioides immitis and Coccidioides posadasii. Upon inhalation, the fungus enters the lungs and converts to the tissue parasitic phase, which consists of alternating spherules and endospores. Infection can be asymptomatic or can cause flulike symptoms, meningitis, or skin, bone or joint manifestations. Diagnosis and treatment are also reviewed.

Chapter.  901 words.  Illustrated.

Subjects: Infectious Diseases

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