Sepsis Syndrome

Andrew D Badley

in Mayo Clinic Infectious Diseases Board Review

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print January 2012 | ISBN: 9780199827626
Published online June 2012 | e-ISBN: 9780199929641 | DOI:

Series: Mayo Clinic Scientific Press

Sepsis Syndrome

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Systemic inflammatory response syndrome (SIRS) is the specific host systemic response that may be elicited by various stimuli, including infection, burns, pancreatitis, ischemia, trauma, hemorrhage, immune-mediated tissue injury, and exogenous stimuli. 2. Sepsis is SIRS resulting from infection. Sepsis syndrome is sepsis with altered tissue perfusion of vital organs (resulting in oliguria, hypoxemia, elevated levels of lactate, or altered mentation or any combination of these conditions) When a patient has SIRS, the objective is to define its cause. If SIRS is caused by infection, appropriate antibiotics must be administered and supportive care guided by the patient's history and physical examination.

Chapter.  2499 words. 

Subjects: Infectious Diseases

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