Chapter

Essential Molecular Biology of Cardiovascular Diseases

Cindy W. Tom and Robert D. Simari

in Mayo Clinic Cardiology

Fourth edition

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print November 2012 | ISBN: 9780199915712
Published online May 2013 | e-ISBN: 9780199322824 | DOI: http://dx.doi.org/10.1093/med/9780199915712.003.0142

Series: Mayo Clinic Scientific Press

Essential Molecular Biology of Cardiovascular Diseases

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Molecular biologic tools are helpful in the diagnosis of cardiovascular diseases. Polymerase chain reaction is a powerful tool for amplifying minute portions of DNA for analysis. Sensitive PCR tests have been developed for various diseases by extracting DNA from a small blood sample. The identification of genes associated with disease has been the focus of an enormous effort in biomedical science. Genetic diseases can be associated with single-gene or multigene abnormalities. Of the many types of diseases that affect the cardiovascular system, an increasing number have been identified as resulting from single-gene (monogenic) or polygenic mutations. Several of these diseases are reviewed.

Chapter.  4135 words.  Illustrated.

Subjects: Cardiovascular Medicine

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