Cardiac Resynchronization Therapy

Grace Lin and David L. Hayes

in Mayo Clinic Cardiology

Fourth edition

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print November 2012 | ISBN: 9780199915712
Published online May 2013 | e-ISBN: 9780199322824 | DOI:

Series: Mayo Clinic Scientific Press

Cardiac Resynchronization Therapy

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Cardiac resynchronization therapy (CRT) is the term applied to reestablishing synchrony between left ventricular free wall and ventricular septal contraction. Approximately one-third of patients with dilated cardiomyopathy also have a conduction delay due to left bundle branch block, resulting in left ventricular dyssynchrony and worsening heart failure. In these patients, CRT may promote left ventricular reverse remodeling and improve symptoms and mortality from heart failure. CRT is achieved through biventricular pacing, with placement of a left ventricular lead in addition to a right ventricular lead. Indications for CRT, implantation techniques, prediction of response, and clinical trials are reviewed in this chapter.

Chapter.  1676 words.  Illustrated.

Subjects: Cardiovascular Medicine

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