Epidemiology of Valvular Heart Diseases

Vuyisile T. Nkomo

in Mayo Clinic Cardiology

Fourth edition

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print November 2012 | ISBN: 9780199915712
Published online May 2013 | e-ISBN: 9780199322824 | DOI:

Series: Mayo Clinic Scientific Press

Epidemiology of Valvular Heart Diseases

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Valvular heart diseases are an important public health problem worldwide. They are classically related to rheumatic fever and rheumatic heart disease. Rheumatic fever and rheumatic heart disease are thought to result from an autoimmune reaction to group A streptococcal pharyngeal infection, which leads initially to valve regurgitation (mitral regurgitation more often than aortic regurgitation) and later to valve stenosis (mitral stenosis more often than aortic stenosis). Although the incidence of rheumatic heart disease has decreased markedly in economically developed countries owing to the dramatic decrease in the incidence of rheumatic fever, rheumatic heart disease persists in economically developing countries owing to the persistently high incidence of rheumatic fever.

Chapter.  1121 words. 

Subjects: Cardiovascular Medicine

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