Journal Article

Recent progress in luteinizing hormone/human chorionic gonadotrophin hormone research

Nafis A. Rahman and C.V. Rao

in MHR: Basic science of reproductive medicine

Published on behalf of European Society of Human Reproduction and Embryology

Volume 15, issue 11, pages 703-711
Published in print November 2009 | ISSN: 1360-9947
Published online August 2009 | e-ISSN: 1460-2407 | DOI: http://dx.doi.org/10.1093/molehr/gap067
Recent progress in luteinizing hormone/human chorionic gonadotrophin hormone research

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The role of luteinizing hormone (LH) and human chorionic gonadotrophin hormone (hCG) in the regulation of normal reproductive functions in males and females is quite well established. Besides the use of hCG in the development of diagnostic immunoassays, it has been successfully used in the induction of final follicular maturation and ovulation in the assisted reproductive technologies. The basic and clinical research on the nongonadal actions of LH/hCG in the recent years has extended the potential of using these hormones in several clinical indications. Hereby we will analyze the advances in the LH/hCG research (briefly emphasizing the nongonadal research), which has the potential for multiple novel therapies in reproductive and the other areas of medicine.

Keywords: luteinizing hormone; human chorionic gonadotrophin; luteinizing/human chorionic gonadotrophin receptor; gonadal and nongonadal effects

Journal Article.  6057 words. 

Subjects: Reproductive Medicine

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