Journal Article

PrDOS: prediction of disordered protein regions from amino acid sequence

Takashi Ishida and Kengo Kinoshita

in Nucleic Acids Research

Volume 35, issue suppl_2, pages W460-W464
Published in print July 2007 | ISSN: 0305-1048
Published online July 2007 | e-ISSN: 1362-4962 | DOI: http://dx.doi.org/10.1093/nar/gkm363
PrDOS: prediction of disordered protein regions from amino acid sequence

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PrDOS is a server that predicts the disordered regions of a protein from its amino acid sequence (http://prdos.hgc.jp). The server accepts a single protein amino acid sequence, in either plain text or FASTA format. The prediction system is composed of two predictors: a predictor based on local amino acid sequence information and one based on template proteins. The server combines the results of the two predictors and returns a two-state prediction (order/disorder) and a disorder probability for each residue. The prediction results are sent by e-mail, and the server also provides a web-interface to check the results.

Journal Article.  2043 words.  Illustrated.

Subjects: Chemistry ; Biochemistry ; Bioinformatics and Computational Biology ; Genetics and Genomics ; Molecular and Cell Biology

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