Journal Article

RNA interference and chemically modified siRNAs

Muthiah Manoharan

in Nucleic Acids Symposium Series

Volume 3, issue 1, pages 115-116
Published in print September 2003 | ISSN: 0261-3166
Published online September 2003 | e-ISSN: 1746-8272 | DOI: https://dx.doi.org/10.1093/nass/3.1.115
RNA interference and chemically modified siRNAs

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RNA interference (RNAi) represents one of the most promising new frontiers in drug discovery. Short double-stranded RNA molecules are able to sequence-specifically inhibit expression of genes. This young technology offers both opportunities and challenges to nucleic acid chemists.

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Subjects: Chemistry ; Bioinformatics and Computational Biology ; Genetics and Genomics ; Molecular and Cell Biology

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