Journal Article

Cardiovascular abnormalities in ageing and in uraemia--only analogy or shared pathomechanisms?

K Amann and E Ritz

in Nephrology Dialysis Transplantation

Volume 13, issue suppl_7, pages 6-11
Published in print January 1998 | ISSN: 0931-0509
Published online January 1998 | e-ISSN: 1460-2385 | DOI: http://dx.doi.org/10.1093/ndt/13.suppl_7.6
Cardiovascular abnormalities in ageing and in uraemia--only analogy or shared pathomechanisms?

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The analogies between the effects of ageing and of uraemia on the function and the structure of central elastic arteries and of the heart are striking. Qualitatively similar changes are seen in pulse contour, pulse wave velocity, and impedance and also similar structural abnormalities with wall thickening, diminished elastin, and increased collagen content. The altered 'Windkessel' function of central arteries in age and uraemia is one factor contributing to left ventricular hypertrophy.

Journal Article.  0 words. 

Subjects: Nephrology

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