Journal Article

The impact of haemofiltration on the systemic cardiovascular response

Antonio Santoro, Elena Mancini and Pietro Zucchelli

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 15, issue suppl_2, pages 49-54
Published in print September 2000 | ISSN: 0931-0509
Published online September 2000 | e-ISSN: 1460-2385 | DOI:
The impact of haemofiltration on the systemic cardiovascular response

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Convective transport across the dialysis membrane has long been known to be a good alternative to diffusion. Among the advantages of haemofiltration over conventional haemodialysis is a better cardiovascular stability. Haemofiltration has a more physiological response to fluid removal than haemodialysis: (i) blood volume may be better preserved, especially in patients with a compromised cardiac function; (ii) arterial peripheral resistances and venous tone increase; and (iii) myocardial contractility is neither depressed nor altered. We discuss the role of the different pathophysiological mechanisms in the disparity in cardiovascular reactivity between haemofiltration and haemodialysis.

Keywords: blood pressure; cardiovascular reactivity; haemodialysis; haemofiltration

Journal Article.  0 words. 

Subjects: Nephrology

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