Journal Article

Renal replacement therapy in Europe: the results of a collaborative effort by the ERA–EDTA registry and six national or regional registries

Paul C. W. van Dijk, Kitty J. Jager, Frank de Charro, Frederic Collart, Ronald Cornet, Friedo W. Dekker, Carola Grönhagen‐Riska, Reinhard Kramar, Torbjørn Leivestad, Keith Simpson and J. Douglas Briggs

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 16, issue 6, pages 1120-1129
Published in print June 2001 | ISSN: 0931-0509
Published online June 2001 | e-ISSN: 1460-2385 | DOI: http://dx.doi.org/10.1093/ndt/16.6.1120
Renal replacement therapy in Europe: the results of a collaborative effort by the ERA–EDTA registry and six national or regional registries

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Background. In June 2000 a new ERA–EDTA Registry Office was opened in Amsterdam. This Registry will only collect core data on renal replacement therapy (RRT) through national and regional registries. This paper reports the technical and epidemiological results of a pilot study combining the data from six registries.

Methods. Data from the national renal registries of Austria, Finland, French‐Belgium, The Netherlands, Norway, and Scotland were combined. Patients starting RRT between 1980 and 1999 (n=57371) were included in the analyses. Cox proportional hazards regression was used to predict survival.

Results. The use of different coding systems for ESRD treatment by the registries made it difficult to merge the data. Incidence and prevalence of RRT showed a continuous increase with a marked variation in rates between countries. The 2‐, 5‐ and 10‐year patient survival was 67, 35 and 11% in dialysis patients and 90, 81 and 64% after a first renal allograft. Multivariate analysis showed a slightly better survival on dialysis in the 1990–1994 (RR 0.94, 95% CI 0.90–0.98) and the 1995–1999 cohort (RR 0.88, 95% CI 0.84–0.92) compared to the 1980–1984 cohort. In contrast, there was a much greater improvement in transplant‐patient survival, resulting in a 56% reduction in the risk of death within the 1995–1999 cohort (RR 0.44, 95% CI 0.39–0.50) compared to the 1980–1984 cohort.

Conclusions. This study provides support for the feasibility of a ‘new style’ ERA–EDTA registry and the collection of data is now being extended to other countries. The improvement in patient survival over the last two decades has been much greater in transplant recipients than in dialysis patients.

Keywords: epidemiology; Europe; mortality; primary renal disease; renal replacement therapy; technique survival

Journal Article.  3318 words.  Illustrated.

Subjects: Nephrology

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