Journal Article

Osseous metaplasia in a kidney allograft

Stanislas Bataille, Laurent Daniel, Tristan Legris, Henri Vacher-Coponat, Raj Purgus, Yvon Berland and Valerie Moal

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 25, issue 11, pages 3796-3798
Published in print November 2010 | ISSN: 0931-0509
Published online August 2010 | e-ISSN: 1460-2385 | DOI: http://dx.doi.org/10.1093/ndt/gfq490
Osseous metaplasia in a kidney allograft

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Osseous metaplasia is defined by the presence of heterotopic normal bone tissue in a soft tissue. The bone matrix is associated with osteoblasts, osteoclasts, adipocytes and haematopoietic stem cells. Osseous metaplasia pathophysiology is not well known, but many factors have been incriminated including chronic inflammation and chronic ischaemia. We describe the second case of osseous metaplasia in a kidney allograft. Numerous factors might favour its development including factors linked to transplantation failure environment.

Keywords: bone; kidney; metaplasia; transplantation

Journal Article.  1255 words.  Illustrated.

Subjects: Nephrology

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