Journal Article

Focal segmental glomerulosclerosis as a complication of hepatitis B virus infection

Kentaro Sakai, Naoki Morito, Joichi Usui, Masahiro Hagiwara, Akira Hiwatashi, Kuniaki Fukuda, Toru Nanmoku, Takayuki Toda, Noriaki Matsui, Michio Nagata and Kunihiro Yamagata

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 26, issue 1, pages 371-373
Published in print January 2011 | ISSN: 0931-0509
Published online October 2010 | e-ISSN: 1460-2385 | DOI: http://dx.doi.org/10.1093/ndt/gfq600
Focal segmental glomerulosclerosis as a complication of hepatitis B virus infection

Show Summary Details

Preview

Human hepatitis B virus (HBV) is well known as a cause of membranous nephropathy (MN). While the association of HBV infection with MN is strong, data regarding its association with other glomerular diseases are conflicting. Here, we report a case of focal segmental glomerulosclerosis (FSGS) with HBV infection. In this case, we have found HBV-DNA in urinary podocytes by real-time PCR methods. After the administration of anti-viral therapy, FSGS improved, paralleling the decreased level of HBV-DNA in podocytes. The refractory FSGS induced by HBV could be effectively treated with appropriate anti-viral agents.

Keywords: anti-viral therapy; focal segmental glomerulosclerosis; human hepatitis B virus

Journal Article.  1227 words.  Illustrated.

Subjects: Nephrology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.