Journal Article

Improving CKD-MBD management in haemodialysis patients: barrier analysis for implementing better practice

Nigel D. Toussaint, Eugenie Pedagogos, Jennifer Beavis, Gavin J. Becker, Kevan R. Polkinghorne and Peter G. Kerr

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 26, issue 4, pages 1319-1326
Published in print April 2011 | ISSN: 0931-0509
Published online October 2010 | e-ISSN: 1460-2385 | DOI:
Improving CKD-MBD management in haemodialysis patients: barrier analysis for implementing better practice

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Background. Although clinical guidelines exist for optimal levels of serum markers of chronic kidney disease mineral and bone disorder (CKD-MBD), target parameters are not achieved in many haemodialysis (HD) patients. The reason for this evidence–practice gap is unclear and more information from patients and healthcare professionals is required to improve knowledge transfer. We aimed to determine potential barriers by surveying HD patients and staff about awareness and management of CKD-MBD.

Methods. A total of 136 prevalent HD patients, 25 nephrologists and 58 dialysis nurses/technicians were surveyed. Three separate questionnaires included issues of knowledge and awareness of CKD-MBD and factors limiting management (including compliance, medications and general understanding).

Results. Of patients surveyed, 84% had heard of phosphate, but 42% were unsure of high phosphate foods and 46% unaware of consequences of elevated phosphate. Twenty-seven percent and thirty-five percent of patients, respectively, had difficulty taking or forgetting to take phosphate binders. Seventy-four percent of patients wanted to know more about CKD-MBD (40% via written material). Of nephrologists surveyed, 76% thought non-compliance with phosphate binders was the main reason for poor control of phosphate (predominantly related to poor patient understanding); 84% thought patients wanted to know more but only 28% provided written material on CKD-MBD. Of dialysis staff surveyed, 63% thought non-compliance with binders explained poor control, the main reason being lack of patient understanding; 88% thought patients wanted to know more but only 17% provided written education.

Conclusions. Implementation of an intensive educational programme, with a multi-faceted approach, for HD patients may promote better control of CKD-MBD and improve achievement of target levels.

Keywords: chronic kidney disease; CKD-MBD; evidence–practice gap; haemodialysis; mineral metabolism

Journal Article.  5752 words. 

Subjects: Nephrology

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