Journal Article

Atypical presentation of atypical amyloid

Danniele G. Holanda, Veena K. Acharya, Ahmet Dogan, Lorraine C. Racusen and Mohamed G. Atta

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 26, issue 1, pages 373-376
Published in print January 2011 | ISSN: 0931-0509
Published online October 2010 | e-ISSN: 1460-2385 | DOI: http://dx.doi.org/10.1093/ndt/gfq638
Atypical presentation of atypical amyloid

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Amyloidosis is a group of diseases categorized by precipitation of a group of protein aggregates (amyloid) in tissues, including the kidney, and proteinuria is usually the commonest, though not exclusive, hallmark of clinical presentation. AL and AA are the most commonly recognized forms of amyloidosis involving the kidney, but other forms have been described. We present a case of renal amyloidosis due to a novel amyloidogenic protein, leucocyte cell-derived chemotaxin 2, without proteinuria at presentation or on subsequent follow-up.

Keywords: ALECT2; amyloidosis; proteinuria

Journal Article.  1142 words.  Illustrated.

Subjects: Nephrology

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