Journal Article

An exceptional minute tumour incidentally found in a renal biopsy

David Buob, Marie-Christine Copin, Thierry Perez, Éric Hachulla, Marc Hazzan and Xavier Leroy

in Nephrology Dialysis Transplantation

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 26, issue 4, pages 1436-1438
Published in print April 2011 | ISSN: 0931-0509
Published online February 2011 | e-ISSN: 1460-2385 | DOI: http://dx.doi.org/10.1093/ndt/gfq836
An exceptional minute tumour incidentally found in a renal biopsy

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Pathological analysis of renal biopsies performed to investigate a nephrological disease may exceptionally reveal incidental tumours, in addition to expected glomerular, tubulointerstitial or vascular pathology. We present the first case to date of a minute angiomyolipoma (AML), found incidentally in a renal biopsy specimen, performed in the assessment of proteinuria. AML is an uncommon kidney tumour, composed of a variable proportion of adipose tissue, spindle and epithelioid smooth muscle cells. Immunohistochemistry is mandatory for a definitive diagnosis, showing a specific perivascular epithelioid differentiation. The diagnosis of renal AML justifies the search for tuberous sclerosis-associated tumours.

Keywords: angiomyolipoma; incidental tumour; tuberous sclerosis

Journal Article.  1252 words.  Illustrated.

Subjects: Nephrology

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