Journal Article

Spontaneous perinephric haemorrhage and acute renal failure in pregnancy due to cocaine intoxication

Chike M. Nzerue, Kehinde Carew, Marquetta Faulkner, Sandra Torrente and Mary Fleming

in Clinical Kidney Journal

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 3, issue 3, pages 265-268
Published in print June 2010 | ISSN: 1753-0784
Published online February 2010 | e-ISSN: 1753-0792 | DOI: http://dx.doi.org/10.1093/ndtplus/sfq015

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Cocaine abuse may contribute to the diverse forms of renal injury. We report a case of a pregnant woman who developed a large subcapsular renal haematoma after cocaine intoxication at 18-week gestation. She stabilized on conservative management and presented again at 29-week gestation with pre-eclampsia, acute renal failure and fetal demise. She required caesarean section delivery and intensive antihypertensive therapy to control severe pre-eclampsia associated with cocaine intoxication. This case is unique in that it is the first report of cocaine intoxication in pregnancy complicated by subcapsular haemorrhage. We discuss the possible mechanisms for the occurrence of this complication.

Keywords: acute renal failure; cocaine abuse; pre-eclampsia; subcapsular haemorrhage

Journal Article.  1824 words.  Illustrated.

Subjects: Nephrology

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