Journal Article

Spontaneous perinephric hematoma due to acquired factor X deficiency in AL amyloidosis

Rupesh Raina, Vidya Nadig, Deven Patel, Armin Jegalian, Bernard Silver and Robert J. Heyka

in Clinical Kidney Journal

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 4, issue 2, pages 101-103
Published in print April 2011 | ISSN: 1753-0784
Published online February 2011 | e-ISSN: 1753-0792 | DOI:

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Spontaneous perinephric hematoma (SPH) is a rare entity whose diagnosis is challenging because of its varied clinical presentation and lack of any specific etiology. We report a 34-year-old African-American male who presented with left flank pain and was found to have a large left perinephric hematoma, in the setting of undiagnosed AL amylodosis. The case illustrates that while a SPH due to the vascular angiopathy of amyloid is rare, when amyloidosis is associated with abnormal coagulation studies or bleeding at multiple sites, it should be considered because of its protean systemic manifestations and potential response to chemotherapy.

Keywords: amyloidosis; spontaneous perinephric hematoma

Journal Article.  1261 words.  Illustrated.

Subjects: Nephrology

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