abdominal aortic aneurysm

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A multifactorial disorder in which there is permanent dilation of the abdominal aorta, usually due to degenerative changes in the aortic wall. There is chronic inflammation of the aortic wall with remodelling of the extracellular matrix, and depletion of vascular smooth muscle cells. Defects in collagen type III are one cause of susceptibility.

Subjects: Medicine and Health.

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