Multisubunit toxins that have an active (A) portion and a portion involved in binding (B) to target cells. The A portion is toxic if introduced directly into the cytoplasm. In several types (cholera toxin, diphtheria toxin, pertussis toxin) the A subunit has ADP-ribosylating activity. See also colicins; Ricinus communis agglutinins; shiga toxin; tetanus toxin; VacA.
Subjects: Medicine and Health.