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ACADs


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Acad

Acad

ACADs

MAUROIS, André (1885 - 1967), Mem. of French Acad., since 1938

Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency

BROWN, Ernest William (1866 - 1938), Corr. Member Inst. France (Acad. Sc.); For. Ass. Mem. Royal Acad. Belgium; Member Nat. Acad. Sc., USA; Professor of Mathematics, Yale University, 1907–32; Emeritus since 1932

BREMOND, L’Abbé Henri (1865 - 1933), Member of the French Acad. since 1923

ABBEY, Edwin Austin (1852 - 1911), Hon. Mem. Royal Bavarian Acad. and Madrid Society of Artists

P502. Predictors of bad response to infliximab in Ulcerative Colitis patients (ECIA study. ACAD)

ACAD9, a complex I assembly factor with a moonlighting function in fatty acid oxidation deficiencies

TOMLINSON, H. M. (1873 - 1958), Hon. mem. Amer. Acad. of Arts and Letters; Officer Brazilian Order of Southern Cross

Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene

CHARCOT, Jean Baptiste Etienne Auguste (1867 - 1936), Grand Officier de la Légion d’Honneur; Membre de l’Institut; Membre de l’Acad. de Medecine et de l’Acad. de Marine; Capitaine de Frigate honoraire; Conseiller Scientifique du Service Hydrographique de la Marine; Directeur du Laboratoire Maritime des Hautes Etudes

BEVERIDGE, Wilfred William Ogilvy (1864 - 1962), late Professor of Hygiene, Royal Army Medical College; late Director of Hygiene, War Office; Corr. Member French Acad. of Medicine

DRURY, Henry Cooke (1860 - 1944), Consulting Physician, Sir P. Dun’s Hospital, Dublin; Consulting Physician, Rotunda Hospital; late Physician, Cork Street Fever Hospital; late FR Acad. Med. I, late FRSAI

ABBE, Cleveland (1838 - 1916), Member, US National Acad. of Science; Professor of Meteorology, US Weather Bureau, since 1871; Lecturer on Meteorology, Johns Hopkins University, since 1895

THOMPSON, D’Arcy Wentworth (1860 - 1948), Professor of Natural History, St Andrews University, in Dundee, 1884–1917, in St Andrews, since 1917; Past President, Classical Association, 1929, Scottish Classical Association, 1935, Royal Phys. Soc. Edin. and Royal Soc. Edin. 1934–39; R. Sc. Geog. Soc. 1942–46; Foreign, Corr. or Hon. Member of Nat. Acad. Sci., USA; Amer. Philos. Soc. (Philadelphia); Amer. Acad. Arts and Sci. (Boston); Polish Acad. (Cracow); Schweiz. Naturf. Ges.; Friends of NH (Moscow); Boston Soc. NH; Soc. Biol. Paris; Soc. Zool. France; Zool. Soc. London; Malacological Soc.; Edin. Mathem. Soc.; Linnean medallist, 1938; David Giraud Elliot medallist, 1942; Darwin Medallist, Royal Soc., 1946; scientific member of Fishery Board for Scotland, 1898–1939

MOORE, Reginald (1910 - 1968), Lecturer in Music, The University of Exeter, 1955–65; Lecturer in Music, 1965; Hon. Local Representative, Roy. Acad. of Music, since 1956; Examr for Associated Bd of Royal Schools of Music, 1958

ROWLEY, Harold Henry (1890 - 1969), Foreign mem., Roy. Flemish Acad.; Mem., Roy. Soc. of Letters of Lund; Hon. Mem., Soc. of Biblical Literature (USA); Hon. Fell., Sch. of Oriental and Afr. Studies, London

 

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A family of mitochondrial enzymes (acyl-coenzyme A dehydrogenases) that catalyse the first dehydrogenation step in the beta-oxidation of fatty acyl-CoA derivatives. There are different ACADs for short-, medium-, long- and very long-chain fatty acids. The product of the ACAD8 gene, also known as isobutyryl-coenzyme A (CoA) dehydrogenase (EC 1.3.99, 415 aa), converts isobutyryl-CoA into succinyl-CoA. At least four mutations in the ACAD8 gene have been identified and lead to isobutyryl-CoA dehydrogenase deficiency in which there may be dilated cardiomyopathy, anaemia, and carnitine deficiency.

Subjects: Medicine and Health.


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