Overview

ASIP


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1. Agouti signalling protein (132 aa), the human homologue of mouse agouti, which inhibits melanogenesis by binding to the melanocyte stimulating hormone (MSH) receptor and blocking α-MSH signalling. Variation in the gene encoding ASIP affects hair and eye pigmentation. ASIP may also affect adipocyte function.

2. Atypical protein kinase C isotype-specific interacting protein interacts with PKC-(lambda and -zeta and when overexpressed, inhibits insulin-induced glucose uptake.

Subjects: Medicine and Health.


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