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An extensive family (A-kinase anchoring protein family) of scaffolding proteins that determine the cellular localization of different protein kinase A isoforms which are tethered through a regulatory subunit. Calcineurin and protein kinase C also bind to some AKAPs; the PKC and calcineurin sites are different, so that both can be bound. See pericentrin.
From: AKAP family in A Dictionary of Biomedicine »
Subjects: Medicine and Health.
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