aldose reductase

'aldose reductase' can also refer to...

aldose reductase

Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor

Inhibition of aldose reductase prevents colon cancer metastasis

Attenuation of ischemia induced increases in sodium and calcium by the aldose reductase inhibitor Zopolrestat

Induction of aldose reductase and xylitol dehydrogenase activities in Candida tenuis CBS 4435

Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation

Reduced 293T Cell Susceptibility to Acrolein Due to Aldose Reductase–like-1 Protein Expression

Effects of Aldose Reductase Inhibitors on Antioxidant Defense in Rat and Rabbit Liver

Osmoregulation of aldose reductase and sorbitol dehydrogenase in cultivated interstitial cells of rat renal inner medulla

Overexpression of the aldose reductase GRE3 suppresses lithium-induced galactose toxicity in Saccharomyces cerevisiae

Feasibility of xylose fermentation by engineered Saccharomyces cerevisiae overexpressing endogenous aldose reductase (GRE3), xylitol dehydrogenase (XYL2), and xylulokinase (XYL3) from Scheffersomyces stipitis

Overexpression of the Aldose Reductase Gene Induces Apoptosis in Pancreatic β-Cells by Causing a Redox Imbalance

LC–MS-MS Characterization of Forced Degradation Products of Fidarestat, a Novel Aldose Reductase Inhibitor: Development and Validation of a Stability-Indicating RP-HPLC Method

(CA)n Dinucleotide repeat polymorphism at the 5′‐end of the aldose reductase gene is not associated with microangiopathy in Caucasians with long‐term diabetes mellitus 1


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One of the monomeric, NADPH-dependent aldoketoreductase family of enzymes (aldehyde reductase 1, EC1.1.1.21, 316 aa) involved in glucose metabolism and osmoregulation. It is the first and rate-limiting enzyme of the polyol pathway of sugar metabolism, has a role in protecting against toxic aldehydes derived from lipid peroxidation and steroidogenesis, and has been implicated in diabetic complications.

Subjects: Medicine and Health.

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