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Aliskiren, ALTITUDE, and the implications for ATMOSPHERE

Diabetes, aliskiren, and heart failure: let's bring ASTRONAUT down to earth

Aliskiren/Amlodipine vs. Aliskiren/Hydrochlorothiazide in Hypertension: Indirect Meta-Analysis of Trials Comparing the Two Combinations vs. Monotherapy

Aliskiren reduces sympathetic nerve activity and blood pressure in chronic kidney disease patients

Aliskiren combined with losartan in immunoglobulin A nephropathy: an open-labeled pilot study

Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design

Aliskiren improves insulin resistance and ameliorates diabetic vascular complications in db/db mice

Neurohumoral effects of the new orally active renin inhibitor, aliskiren, in chronic heart failure

Aliskiren vs. Angiotensin Receptor Blockers in Hypertension: Meta-Analysis of Randomized Controlled Trials

P080 The Protective Effects of Aliskiren on Lung Histopathology after Triolein-Induced Fat Embolism

Differential Effects of Aliskiren/Amlodipine Combination and High-Dose Amlodipine Monotherapy on Endothelial Function in Elderly Hypertensive Patients

Simultaneous Determination of Aliskiren Hemifumarate, Amlodipine Besylate and Hydrochlorothiazide in Spiked Human Plasma Using UPLC-MS/MS

Rationale and design of the multicentre, randomized, double-blind, placebo-controlled Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT)

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Aliskiren alone or with other antihypertensives in the elderly with borderline and stage 1 hypertension: the APOLLO trial

Determination of Aliskiren in Tablet Dosage Forms by a Validated Stability-indicating RP-LC Method

A Validated LC Method for the Determination of the Enantiomeric Purity of Aliskiren Hemifumarate in Bulk Drug Samples

P077 Aliskiren, a Direct Renin Inhibitor, Reduces Mast Cell Accumulation in Lungs of Rats After Fat Embolism


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Quick Reference

The first renin inhibitor developed; used to treat essential hypertension. Crystal structure analyses of renin–inhibitor complexes combined with computational methods were used in the design process. TNs Rasilez, Tekturna.

Subjects: Clinical Pharmacology and Therapeutics.

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