allele-specific oligonucleotide testing

'allele-specific oligonucleotide testing' can also refer to...


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A technique used to identify a specific mutation in a collection of DNA fragments isolated from a mutant organism. An oligonucleotide is synthesized that has a base sequence complementary to the segment under study, and it is used as a probe. All segments binding to the probe are then collected and analyzed.

Subjects: Genetics and Genomics.

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