alpha galactosidase

Quick Reference

An enzyme that catalyzes the hydrolysis of substrates that contain α-galactosidic residues, including glycosphingolipids and glycoproteins. In humans, α-galactosidase exists in two forms, A and B. The A form is encoded by a gene on the X chromosome. Fabry disease (q.v.) is caused by mutations at this locus. The B form is encoded by a gene on chromosome 22.

Subjects: Genetics and Genomics.

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