Overview

amphiregulin


Show Summary Details

Quick Reference

A heparin-binding growth factor (Schwannoma-derived growth factor, 84 aa) containing an EGF-like domain. Binds to the EGF receptor, though with lower affinity than EGF, stimulates proliferation of human fibroblasts, and inhibits growth of some, but not all, human tumour cells. Expression is increased in psoriatic epidermis. See heparin-binding epidermal growth factor.

Subjects: Medicine and Health — Chemistry.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.