Overview

amphiphysin


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A synaptic vesicle-associated protein (695 aa) that forms a heterodimer with bridging integrator 1 (BIN1, amphiphysin-2, Myc box-dependent-interacting protein 1, 593 aa) which binds to synaptojanin-1, dynamin 1, clathrin, and adapter-related protein complex 2 and may regulate the release of synaptic vesicles. Antibodies against amphiphysin are found in patients with stiff person syndrome. See BAR proteins.

Subjects: Medicine and Health — Chemistry.


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