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n. a rare manifestation of longstanding or partially treated infection due to Entamoeba histolytica, leading to development of a nonmalignant tumour-like (pseudotumorous) inflammatory mass. It can occur in the caecum, appendix, and rectosigmoid area in descending order of frequency. These pseudotumours may ulcerate and become infected with pus-forming (pyogenic) bacteria, causing severe inflammation of the bowel wall. They can cause symptoms of intestinal obstruction, weight loss, and low-grade fever. Colonic amoeboma with multiple amoebic liver abscesses can masquerade as colorectal carcinoma and liver metastases; imaging with ultrasound and CT scan is used to differentiate between these.

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