Cells (or in vitro cell cultures) that will grow, survive, or maintain function only when attached to an inert surface such as glass or plastic; also known as substrate-dependent cells. The only normal animal cells that are designed to survive without attachment and spreading are cells that circulate in the blood. Some tumor cells acquire this ability to be anchorage-independent and leave their original tissue sites to form metastases. See microcarriers, suspension culture.
Subjects: Genetics and Genomics.