androgen receptor

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A protein belonging to a subfamily of steroid hormone receptors within a larger family of DNA-binding proteins. The human AR is made up of 919 amino acids and is subdivided into three domains. The N-terminal domain has a regulatory function, and the C-terminal domain binds dihydrotestosterone. The central domain, which binds to DNA, contains zinc fingers. The receptor binds to DNA as a homodimer. See androgen, testosterone, vitamin D receptor, zinc finger protein.

Subjects: Chemistry — Genetics and Genomics.

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