androgen receptor gene

'androgen receptor gene' can also refer to...


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A gene symbolized AR that is located on the X chromosome at q12. It contains eight exons and is 180,245 bp long. AR encodes the androgen receptor (q.v.). Homologous genes occur in the rat and mouse. Mutations in critical portions of AR cause the loss of receptor activity, and this results in abnormalities in sexual phenotype referred to as androgen insensitivity syndrome (q.v.) or testicular feminization. See Chronology, 1988, Brown et al.

Subjects: Genetics and Genomics.

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