antigen-antibody complex

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The product of the interaction between antigen and immunoglobulin. A polyvalent antigen can bind to more than one antibody and the immune complex tends to be large and insoluble and may accumulate in the kidney (see glomerulonephritis). Immune complexes will activate the classical complement pathway. See Arthus reaction; hypersensitivity (type III).

Subjects: Medicine and Health — Chemistry.

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