Overview

AP2


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'AP2' can also refer to...

AP2

CD2AP

CD2AP

AP1S2-Associated XLID (MRX59, AP1S2 Spectrum, Turner XLID Syndrome, Fried Syndrome, XLID-Hydrocephaly-Basal Ganglia Calcification)

Ap(h)thonius (RE 2), Aelius Festus

HD 97394: a magnetic Ap star with high cerium overabundance2

Turner XLID (See also AP1S2-Associated XLID) (MRX59, Fried Syndrome, XLID-Hydrocephaly-Basal Ganglia Calcification)

Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling

GAS41 interacts with transcription factor AP-2β and stimulates AP-2β-mediated transactivation

The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems

Gene Structures, Classification and Expression Models of the AP2/EREBP Transcription Factor Family in Rice

Transcription factor AP2 regulates human inhibin α subunit gene expression during in vitro trophoblast differentiation

Transcriptional activation by AP‐2α is modulated by the oncogene DEK

AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin

PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation

XLID-Hydrocephaly-Basal Ganglia Calcifications (See also AP1S2-Associated XLID) (MRX59, Fried Syndrome, Turner XLID)

CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS)

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction

AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis

 

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1. A family of cis-acting transcription activators often expressed in the same cell lineages but at different times or sites in the developing embryo. All bind to the same consensus sequence in DNA. Mutations in AP2-alpha (436 aa) cause branchiooculofacial syndrome. AP2-beta and -gamma bind to the same DNA consensus sequence; AP2-beta (460 aa) is involved in control of differentiation of neuroectodermally derived cells and is mutated in Char's syndrome; AP2-gamma (450 aa) and AP2-delta (452 aa) are also known.

2. See adaptor proteins.

Subjects: Medicine and Health.


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