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apopain


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A peptidase (caspase 3, Yama protein, SCA-1, EC 3.4.22.56), produced by proteolytic cleavage of a precursor (277 aa), that is involved in initiating apoptosis by cleaving poly(ADP-ribose) polymerase (PARP). Will cleave and activate sterol regulatory element binding proteins (SREBPs); caspases 6, 7, and 9; and huntingtin.

Subjects: Medicine and Health — Chemistry.


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