arachidonate 5-lipoxygenase

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EC; other names: 5‐lipoxygenase; leukotriene‐A4 synthase; a lipoxygenase (def. 2) enzyme that catalyses the reaction of arachidonate with dioxygen to form (6E,8Z,11Z,14Z)−(5S)‐5‐hydroperoxyeicosa‐6,8,11,14‐tetraenoate. Iron is a cofactor.

Subjects: Chemistry.

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