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A genetic disease affecting the metabolism of the amino acid arginine, and hence the normal formation of urea as the end-product of protein metabolism. Depending on the severity of the condition, affected infants may become comatose and die after a moderately high intake of protein. Treatment is by severe restriction of protein intake. Sodium benzoate may be given to increase the excretion of nitrogenous waste as hippuric acid. See also benzoic acid.

Subjects: Medicine and Health.

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