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A class I small leucine-rich repeat proteoglycan (periodontal ligament-associated protein 1, PLAP1, 380 aa) that has a unique stretch of aspartate residues at its N-terminus. The sequence has homology with decorin and biglycan and is associated with skeletal tissues. An allele with an increased number of Asp repeats seems to be associated with susceptibility to osteoarthritis.

Subjects: Medicine and Health.

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