An inflammatory disease of the airways that involves eosinophil infiltration and airway remodelling. Asthmatic attacks can be triggered by allergic responses, physical exertion, inhaled chemicals, or stress. Multiple loci and candidate genes have been implicated in susceptibility to asthma and related traits, including variations in the prostaglandin D receptor, IL-1 receptor-associated kinase, various G-protein-coupled receptors, etc.; 50–80% of individuals with atopic dermatitis develop asthma.
Subjects: Medicine and Health.