AT hook

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A small DNA-binding motif centred around a Gly–Arg–Pro tripeptide that binds in the minor groove of AT-rich regions. AT hooks are found in various proteins, including the high-mobility group proteins, and probably work in conjunction with other binding motifs.

http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=147871&blobtype=pdf Article on AT hooks in DNA-binding proteins.

Subjects: Medicine and Health.

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