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azacytosine


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An analogue of cytosine, in which carbon 5 is replaced by a nitrogen. Azacytidine (5-azacytidine, β-ribofuranosyl 5-azacytidine) is the ribonucleoside. 5-Aza-2′-deoxycytidine was developed as a potential antineoplastic drug which can become incorporated into DNA and inhibits DNA methylation. Experimentally often used as an inhibitor of methylation.

Subjects: Medicine and Health.


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