An analogue of cytosine, in which carbon 5 is replaced by a nitrogen. Azacytidine (5-azacytidine, β-ribofuranosyl 5-azacytidine) is the ribonucleoside. 5-Aza-2′-deoxycytidine was developed as a potential antineoplastic drug which can become incorporated into DNA and inhibits DNA methylation. Experimentally often used as an inhibitor of methylation.
Subjects: Medicine and Health.